Clinical research

Clinical research

Functional Gut Diagnostics is committed to carrying out research and development in order to improve current diagnostic practices, produce new diagnostic tests and contribute to knowledge in the field of gastrointestinal physiology.

We currently perform in-house research and audit activity to improve our practices and technology in order to produce more accurate, sensitive and specific testing.  Recent projects have included interrogating our own hydrogen and methane breath test protocols, in turn contributing to national efforts to standardise this test.

In conjunction with our sister company The Functional Gut Clinic, we welcome research collaborations with other healthcare providers, pharmaceutical, medical device and biotechnology companies.

We are currently involved in several collaborative research projects and are recruiting for some of them, so if you have patients that may be suitable, please let us know or get the patient to contact us directly.


Multicentre study with the Functional Gut Clinic London and Manchester as study sites – Randomised, double blind, placebo controlled multi-centre study to assess the efficacy tolerability and safety of Enterosgel in the treatment of irritable bowel syndrome with diarrhoea (IBS-D) in adults.
ISRCTN Number: 17149988
Status – Recruiting


Functional Gut Clinic sponsored investigator led study – The effect of a multi-strain live bacteria supplement on the gut microbiota composition of healthy adults: an open label trial.
IRAS Reference:  264135
Status – Recruiting


Functional Gut Clinic sponsored investigator led study – The effect of an intestinal adsorbent on gases measured in the breath, in patients taking proton pump inhibitors.
IRAS Reference: 264135
Status – Recruiting


Functional Gut Clinic sponsored investigator led study – The use of antacids and alginates during pre-investigation proton pump inhibitor washout: impact on compliance and symptom burden (PPI-washout).
Status: Undergoing regulatory review


Functional Gut Clinic sponsored investigator led study in collaboration with Sheffield Teaching Hospitals NHS Foundation Trust.
IRAS ID: 251209
Status:  Undergoing regulatory review


If you are interested in Functional Gut Diagnostics producing a research protocol, conducting research on your behalf or see us as a suitable site for a research project, please get in touch and we would be happy to discuss this with you.